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Welcome to the breaking news section for GuidelinesNow.ca.
Click on the following links for more information:
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UPLIFT TRIAL
In this randomized, double-blind trial, the researchers compared 4 years of therapy with either
tiotropium or placebo in patients with COPD who were permitted to use all respiratory
medications except inhaled anticholinergic drugs. Of a total of 5993 patients
(mean age, 65+/-8 years) with a mean FEV(1) of 1.32+/-0.44 liters after bronchodilation
(48% of predicted value), the researchers randomly assigned 2987 to the tiotropium group
and 3006 to the placebo group. The researchers conclusion of the study showed that in
patients with COPD, therapy with tiotropium was associated with improvements in lung
function, quality of life, and exacerbations during a 4-year period but did not
significantly reduce the rate of decline in FEV(1). To view a slide set with more
details on this study, please click here.
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Urban Air Pollution and Exacerbations of COPD Study
This study examined visits to the Emergency Respiratory Department as a direct
result of short-term exposure to air pollution and investigated the relationship
between the daily number of COPD emergency room visits and the daily environmental
air concentrations of atmospheric pollutants. To view more details on this study,
please click here.
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